BREVE REVISIÓN SOBRE EL MANEJO FARMACOLÓGICO DE LA DISLIPIDEMIA
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Abstract
The increase and imbalance of cholesterol and triglyceride in the blood are known as dyslipidemia, which is a pathology that triggers health problems called hypercholesterolemia or hypertriglyceridemia, although hyperchylomicronemia or a decrease in high-density cholesterol could also occur. Dyslipidemia can be accompanied by alterations such as type 2 diabetes mellitus (DM-2), gout, hormonal alterations, alcoholism, chronic renal failure, hypothyroidism, metabolic syndrome and is one of the adverse effects of some drugs such as thiazide diuretics, progestin-only, second-generation progestin, danazol, isotretinoin, acitretin, cyclosporine, azathioprine, sirolimus, amprenavir, indinavir, nelfinavir, ritonavir, saquinavir, clozapine, carbamazepine, phenobarbital, and phenytoin. Currently there are many pharmacological treatments for dyslipidemia, for example, it can be treated with many drugs such as statins, fibrates, bile acid sequestrants, ecetimibe and nicotinic acid. The treatment of dyslipidemia with statins is highlighted because they are very effective, and are capable of reducing LDL, TG, CV mortality, and they raise HDL to a small extent.
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